Do I focus solely on the ones in the direct area that my brokerage is? Or can I market myself to those outside of it as well?
I'd focus on
the ones that are unhappy with their current surroundings. It may well be that none of them are going to be moving in the next 10 years, despite the fact that you are now in the business.
You're lucky that you have so many Friends. The best you can do is make sure that sooner, or later, they come to know that you're in the business. And periodically allow the subject of Real Estate to drift into your conversations with them.
Don't mistake a casual interest in the subject to be an indication that they're ready to list, or look at listings.
Everyone has a casual interest in Real Estate. If they're not receptive, then let it drift back out as fast as it came in.
Everyone lives in Real Estate; but not everyone is a prospect for buying or selling anytime in the foreseeable future . . . .
and there's nothing you can do to change that.